WHAT ARE THE EFFECTS OF THIS DRUG?
↑ Median gain 2.64 pounds in 6 to 12 months in a systematic analysis of 8 studies (36)
Beta-blockers increased risk of developing diabetes by 48% [1.48X (1.48 times)]. Nazarzadeh M et al, 2021, Lancet, meta-analysis (2137) and comment by Volpe M et al, 2022 European Heart Journal (2125)
Several studies have found type 2 diabetes to be a risk equivalent for heart disease. We can safely claim that having diabetes is a significant risk factor for heart disease. (1606-1624)
Beta-blockers change carbohydrate metabolism, increase blood sugar levels, reduce tissue insulin sensitivity, and increase triglyceride (TG) concentrations while reducing HDL cholesterol (the good heart protective type of cholesterol). (592, 593, 2128)
Generic Name: Penbutolol