Xigduo XR

WHAT ARE THE EFFECTS OF THIS DRUG?
↓ or Generally weight neutral and sometimes mild weight loss for metformin when given alone (672)
↓ Weight loss of 2.42 pounds average vs placebo (no drug) time not specified in Meta-analysis study for metformin when given alone(700)
↓ Weight 1 to 3.4% (up to 6.6 pounds) at 24 weeks for Dapagliflozin given alone (576)
↓ Weight loss may plateau after 26-34 weeks with Dapagliflozin given alone (568)
* Warnings for Dapagliflozin and (SGLT2) Inhibitors:
↑ Ketoacidosis risk (difficulty breathing, vomiting, abdominal pain, confusion, sleepiness)
↑ Risks of serious UTI (urinary tract infections) and
↑ Risk of bone fractures
↑ Risk of necrotizing fasciitis of the perineum (Fournier gangrene) is rare but potentially fatal.
Generic Name: Dapagliflozin &
Metformin

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