WHAT ARE THE EFFECTS OF THIS DRUG?
↑ Greater than 7% weight gain in 8.5% of people if dose is 1.5 mg per day (1557, 1560)
↑ Greater than 7% weight gain in 10.7% of people if dose is 3 mg per day (1557, 1560)
↑ Greater than 7% weight gain in 4.9% of people if dose is 4.5 mg per day (1557, 1560)
↑ Greater than 7% weight gain in 33% of people if dose is 4.5 mg per day in 48 weeks (1557, 1559)
↑ Greater than 7% weight gain in 12% of people on average in 48 week study (1557, 1559)
↓ Greater than 7% weight loss in 8% of people if dose is 4.5 mg per day in 48 weeks (1557, 1559)
↑ NNH (Number Needed to Harm) for 7% weight gain is 12 to 35 adults taking Cariprazine (1557, 1560)
↑ If 12 to 35 people take Cariprazine (Vraylar) at least one will experience greater than 7% weight gain. (1557)
↑ 72% of people taking 2nd generation antipsychotics gained 7% or more of their baseline weight in greater than > 38 weeks p<0.001 [Meta-analysis of 307 studies (56)]
↑ Virtually all antipsychotic medications are associated weight gain over time. [Meta-analysis of 307 studies (56)] and [Meta-analysis of 81 studies (67)] and (2200, 2190, 2208)
↑ Both 1st and 2nd generation antipsychotics are associated with weight gain. [Meta-analysis of 81 studies (67)]
Generic Name: Cariprazine