WHAT ARE THE EFFECTS OF THIS DRUG?
↓ or Generally weight neutral and sometimes mild weight loss for metformin when given alone (672)
↓ Weight loss of 2.42 pounds average vs placebo (no drug) time not specified in Meta-analysis study for metformin when given alone(700)
↓ Weight loss of 5.3-5.5 pounds at 52 weeks (577) with Empagliflozin given alone - loss may plateau at 26-34 weeks (568)
* FDA Warnings for Empagliflozin and (SGLT2) Inhibitors:
↑ Ketoacidosis risk (difficulty breathing, vomiting, abdominal pain, confusion, sleepiness) and
↑ Risks of serious UTI (urinary tract infections) and
↑ Risk of bone fractures
↑ Risk of necrotizing fasciitis of the perineum (Fournier gangrene) is rare but potentially fatal.
Generic Name: Empagliflozin &
Metformin