WHAT ARE THE EFFECTS OF THIS DRUG?
↓ Wt−4.1%, −4.2% at 104 weeks (575)
↓ Weight loss plateaus after 26 to 34 weeks (568)
* Warnings:
↑ Ketoacidosis risk (difficulty breathing, vomiting, abdominal pain, confusion, sleepiness)
↑ Risks of serious UTI (urinary tract infections)
↑ Bone fractures
↑ Risk of acute kidney injury
↑ Increase in leg and foot amputations (mostly affecting the toes)
↑ Risk of necrotizing fasciitis of the perineum (Fournier gangrene) is rare but potentially fatal.
Generic Name: Canagliflozin